Congenital Heart Block Maternal Sera Autoantibodies Target an Extracellular Epitope on the α(1G) T-Type Calcium Channel in Human Fetal Hearts

BACKGROUND: Congenital heart block (CHB) is a transplacentally acquired autoimmune disease associated with anti-Ro/SSA and anti-La/SSB maternal autoantibodies and is characterized primarily by atrioventricular (AV) block of the fetal heart. This study aims to investigate whether the T-type calcium c...

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Detalles Bibliográficos
Autores principales: Strandberg, Linn S., Cui, Xuezhi, Rath, Arianna, Liu, Jie, Silverman, Earl D., Liu, Xiaoru, Siragam, Vinayakumar, Ackerley, Cameron, Su, Brenda Bin, Yan, Jane Yuqing, Capecchi, Marco, Biavati, Luca, Accorroni, Alice, Yuen, William, Quattrone, Filippo, Lung, Kalvin, Jaeggi, Edgar T., Backx, Peter H., Deber, Charles M., Hamilton, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767782/
https://www.ncbi.nlm.nih.gov/pubmed/24039792
http://dx.doi.org/10.1371/journal.pone.0072668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767782/
https://www.ncbi.nlm.nih.gov/pubmed/24039792
http://dx.doi.org/10.1371/journal.pone.0072668

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