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A Bmi1-miRNAs Cross-Talk Modulates Chemotherapy Response to 5-Fluorouracil in Breast Cancer Cells

The polycomb group transcriptional modifier Bmi1 is often upregulated in numerous cancers and is intensely involved in normal and cancer stem cells, and importantly is as a prognostic indicator for some cancers, but its role in breast cancer remains unclear. Here, we found Bmi1 overexpression in 5-F...

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Detalles Bibliográficos
Autores principales: Yin, Jiang, Zheng, Guopei, Jia, Xiaoting, Zhang, Zhijie, Zhang, Weijia, Song, Ying, Xiong, Yan, He, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767789/
https://www.ncbi.nlm.nih.gov/pubmed/24039897
http://dx.doi.org/10.1371/journal.pone.0073268