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Epimorphin-Induced MET Sensitizes Ovarian Cancer Cells to Platinum

Distinctive genotypic and phenotypic features of ovarian cancer via epithelial-mesenchymal transition (EMT) have been correlated with drug resistance and disease recurrence. We investigated whether therapeutic reversal of EMT could re-sensitize ovarian cancer cells (OCCs) to existing chemotherapy. W...

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Detalles Bibliográficos
Autores principales: Yew, Kok-Hooi, Crow, Jennifer, Hirst, Jeff, Pressetto, Ziyan, Godwin, Andrew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767807/
https://www.ncbi.nlm.nih.gov/pubmed/24039787
http://dx.doi.org/10.1371/journal.pone.0072637