The Diuretic Torasemide Does Not Prevent Aldosterone-Mediated Mineralocorticoid Receptor Activation in Cardiomyocytes

Aldosterone binds to the mineralocorticoid receptor (MR) and exerts pleiotropic effects beyond enhancing renal sodium reabsorption. Excessive mineralocorticoid signaling is deleterious during the evolution of cardiac failure, as evidenced by the benefits provided by adding MR antagonists (MRA) to st...

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Detalles Bibliográficos
Autores principales: Gravez, Basile, Tarjus, Antoine, Jimenez-Canino, Ruben, El Moghrabi, Soumaya, Messaoudi, Smail, de la Rosa, Diego Alvarez, Jaisser, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767808/
https://www.ncbi.nlm.nih.gov/pubmed/24040049
http://dx.doi.org/10.1371/journal.pone.0073737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767808/
https://www.ncbi.nlm.nih.gov/pubmed/24040049
http://dx.doi.org/10.1371/journal.pone.0073737

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