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LPS-Induced proNGF Synthesis and Release in the N9 and BV2 Microglial Cells: A New Pathway Underling Microglial Toxicity in Neuroinflammation

PURPOSE: While aberrant activation of microglial cells was evidently involved in neuroinflammation and neurotoxicity in the neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, objective of study was to address if activated microglias deliver their effect by releasing pro-neurotro...

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Detalles Bibliográficos
Autores principales: Duan, Li, Chen, Bei-Yu, Sun, Xiao-Long, Luo, Zhuo-Jing, Rao, Zhi-Ren, Wang, Jing-Jie, Chen, Liang-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767823/
https://www.ncbi.nlm.nih.gov/pubmed/24040063
http://dx.doi.org/10.1371/journal.pone.0073768