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LPS-Induced proNGF Synthesis and Release in the N9 and BV2 Microglial Cells: A New Pathway Underling Microglial Toxicity in Neuroinflammation
PURPOSE: While aberrant activation of microglial cells was evidently involved in neuroinflammation and neurotoxicity in the neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, objective of study was to address if activated microglias deliver their effect by releasing pro-neurotro...
Autores principales: | Duan, Li, Chen, Bei-Yu, Sun, Xiao-Long, Luo, Zhuo-Jing, Rao, Zhi-Ren, Wang, Jing-Jie, Chen, Liang-Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767823/ https://www.ncbi.nlm.nih.gov/pubmed/24040063 http://dx.doi.org/10.1371/journal.pone.0073768 |
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