HIV-1 Envelope Glycoprotein Resistance to Monoclonal Antibody 2G12 Is Subject-Specific and Context-Dependent in Macaques and Humans

HIV-1 Envelope (Env) protein is the sole target of neutralizing antibodies (NAbs) that arise during infection to neutralize autologous variants. Under this immune pressure, HIV escape variants are continuously selected and over the course of infection Env becomes more neutralization resistant. Many...

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Detalles Bibliográficos
Autores principales: Malherbe, Delphine C., Sanders, Rogier W., van Gils, Marit J., Park, Byung, Gomes, Michelle M., Schuitemaker, Hanneke, Barnett, Susan, Haigwood, Nancy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767832/
https://www.ncbi.nlm.nih.gov/pubmed/24040404
http://dx.doi.org/10.1371/journal.pone.0075277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767832/
https://www.ncbi.nlm.nih.gov/pubmed/24040404
http://dx.doi.org/10.1371/journal.pone.0075277

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