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HIV-1 Envelope Glycoprotein Resistance to Monoclonal Antibody 2G12 Is Subject-Specific and Context-Dependent in Macaques and Humans
HIV-1 Envelope (Env) protein is the sole target of neutralizing antibodies (NAbs) that arise during infection to neutralize autologous variants. Under this immune pressure, HIV escape variants are continuously selected and over the course of infection Env becomes more neutralization resistant. Many...
Autores principales: | Malherbe, Delphine C., Sanders, Rogier W., van Gils, Marit J., Park, Byung, Gomes, Michelle M., Schuitemaker, Hanneke, Barnett, Susan, Haigwood, Nancy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767832/ https://www.ncbi.nlm.nih.gov/pubmed/24040404 http://dx.doi.org/10.1371/journal.pone.0075277 |
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