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Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer
The C-terminal binding protein (CtBP) is a NADH-dependent transcriptional repressor that links carbohydrate metabolism to epigenetic regulation by recruiting diverse histone modifying complexes to chromatin. Here, global profiling of CtBP in breast cancer cells reveals that it drives epithelial to m...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768144/ https://www.ncbi.nlm.nih.gov/pubmed/23385593 http://dx.doi.org/10.1038/ncomms2438 |