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Effect of branched-chain amino acids, valine, isoleucine and leucine on the biosythesis of bitespiramycin 4"-O-acylspiramycins

Bitespiramycin, a group of 4"-O-acylated spiramycins with 4"-O-isovalerylspiramycins as the major components, was produced by recombinant spiramycin-producing strain Streptomyces spiramyceticus harboring a 4"-O-acyltransferase gene. The experiment was initially performed in synthetic...

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Detalles Bibliográficos
Autores principales: Li, Zhen-Lin, Wang, Yong-Hong, Chu, Ju, Zhuang, Ying-Ping, Zhang, Si-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Microbiologia 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768584/
https://www.ncbi.nlm.nih.gov/pubmed/24031420
http://dx.doi.org/10.1590/S1517-83822009000400003