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Response surface methodology for optimization of production of lovastatin by solid state fermentation
Lovastatin, an inhibitor of HMG-CoA reductase, was produced by solid state fermentation (SSF) using a strain of Aspergillus terreus UV 1718. Different solid substrates and various combinations thereof were evaluated for lovastatin production. Wheat bran supported the maximum production (1458 ± 46 µg...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Sociedade Brasileira de Microbiologia
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3768617/ https://www.ncbi.nlm.nih.gov/pubmed/24031477 http://dx.doi.org/10.1590/S1517-838220100001000024 |