Integrated Conformational and Lipid-Sensing Regulation of Endosomal ArfGEF BRAG2

The mechanisms whereby guanine nucleotide exchange factors (GEFs) coordinate their subcellular targeting to their activation of small GTPases remain poorly understood. Here we analyzed how membranes control the efficiency of human BRAG2, an ArfGEF involved in receptor endocytosis, Wnt signaling, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Aizel, Kaheina, Biou, Valérie, Navaza, Jorge, Duarte, Lionel V., Campanacci, Valérie, Cherfils, Jacqueline, Zeghouf, Mahel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769224/
https://www.ncbi.nlm.nih.gov/pubmed/24058294
http://dx.doi.org/10.1371/journal.pbio.1001652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769224/
https://www.ncbi.nlm.nih.gov/pubmed/24058294
http://dx.doi.org/10.1371/journal.pbio.1001652

Ejemplares similares