Unisexual and Heterosexual Meiotic Reproduction Generate Aneuploidy and Phenotypic Diversity De Novo in the Yeast Cryptococcus neoformans

Aneuploidy is known to be deleterious and underlies several common human diseases, including cancer and genetic disorders such as trisomy 21 in Down's syndrome. In contrast, aneuploidy can also be advantageous and in fungi confers antifungal drug resistance and enables rapid adaptive evolution....

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Detalles Bibliográficos
Autores principales: Ni, Min, Feretzaki, Marianna, Li, Wenjun, Floyd-Averette, Anna, Mieczkowski, Piotr, Dietrich, Fred S., Heitman, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769227/
https://www.ncbi.nlm.nih.gov/pubmed/24058295
http://dx.doi.org/10.1371/journal.pbio.1001653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769227/
https://www.ncbi.nlm.nih.gov/pubmed/24058295
http://dx.doi.org/10.1371/journal.pbio.1001653

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