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The Non-Structural NS1 Protein Unique to Respiratory Syncytial Virus: A Two-State Folding Monomer in Quasi-Equilibrium with a Stable Spherical Oligomer

Human respiratory syncytial virus (hRSV) is a major infectious agent that cause pediatric respiratory disease worldwide. Considered one of the main virulence factors of hRSV, NS1 is known to suppress type I interferon response and signaling, thus favoring immune evasion. This, together with the fact...

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Detalles Bibliográficos
Autores principales: Pretel, Esteban, Camporeale, Gabriela, de Prat-Gay, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769240/
https://www.ncbi.nlm.nih.gov/pubmed/24058549
http://dx.doi.org/10.1371/journal.pone.0074338