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Resequencing of Treponema pallidum ssp. pallidum Strains Nichols and SS14: Correction of Sequencing Errors Resulted in Increased Separation of Syphilis Treponeme Subclusters

BACKGROUND: Treponema pallidum ssp. pallidum (TPA), the causative agent of syphilis, is a highly clonal bacterium showing minimal genetic variability in the genome sequence of individual strains. Nevertheless, genetically characterized syphilis strains can be clearly divided into two groups, Nichols...

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Detalles Bibliográficos
Autores principales: Pětrošová, Helena, Pospíšilová, Petra, Strouhal, Michal, Čejková, Darina, Zobaníková, Marie, Mikalová, Lenka, Sodergren, Erica, Weinstock, George M., Šmajs, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769245/
https://www.ncbi.nlm.nih.gov/pubmed/24058545
http://dx.doi.org/10.1371/journal.pone.0074319