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Mechanical Ventilation Enhances HMGB1 Expression in an LPS-Induced Lung Injury Model
BACKGROUND: Mechanical ventilation (MV) can augment inflammatory response in lipopolysaccharide (LPS) challenged lungs. High mobility group box 1 protein (HMGB1) is a pro-inflammatory mediator in ventilator-induced lung injury, but its mechanisms are not well defined. This study investigated the rol...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769250/ https://www.ncbi.nlm.nih.gov/pubmed/24058610 http://dx.doi.org/10.1371/journal.pone.0074633 |