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Mechanical Ventilation Enhances HMGB1 Expression in an LPS-Induced Lung Injury Model

BACKGROUND: Mechanical ventilation (MV) can augment inflammatory response in lipopolysaccharide (LPS) challenged lungs. High mobility group box 1 protein (HMGB1) is a pro-inflammatory mediator in ventilator-induced lung injury, but its mechanisms are not well defined. This study investigated the rol...

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Detalles Bibliográficos
Autores principales:	Ding, Ning, Wang, Fang, Xiao, Hui, Xu, Lixin, She, Shouzhang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769250/ https://www.ncbi.nlm.nih.gov/pubmed/24058610 http://dx.doi.org/10.1371/journal.pone.0074633

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