Cargando…

A Wisp3 Cre-knockin Allele Produces Efficient Recombination in Spermatocytes during Early Prophase of Meiosis I

Individuals with the autosomal recessive skeletal disorder Progressive Pseudorheumatoid Dysplasia have loss-of-function mutations in WISP3, and aberrant WISP3 expression has been detected in tumors from patients with colon and breast cancer. In mice however, neither absence nor over-expression of WI...

Descripción completa

Detalles Bibliográficos
Autores principales: Hann, Steven, Kvenvold, Laura, Newby, Brittney N., Hong, Minh, Warman, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769254/
https://www.ncbi.nlm.nih.gov/pubmed/24040393
http://dx.doi.org/10.1371/journal.pone.0075116