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A Wisp3 Cre-knockin Allele Produces Efficient Recombination in Spermatocytes during Early Prophase of Meiosis I
Individuals with the autosomal recessive skeletal disorder Progressive Pseudorheumatoid Dysplasia have loss-of-function mutations in WISP3, and aberrant WISP3 expression has been detected in tumors from patients with colon and breast cancer. In mice however, neither absence nor over-expression of WI...
Autores principales: | Hann, Steven, Kvenvold, Laura, Newby, Brittney N., Hong, Minh, Warman, Matthew L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769254/ https://www.ncbi.nlm.nih.gov/pubmed/24040393 http://dx.doi.org/10.1371/journal.pone.0075116 |
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