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Stepwise Assembly of Fibrinogen Is Assisted by the Endoplasmic Reticulum Lectin-Chaperone System in HepG2 Cells

The endoplasmic reticulum (ER) plays essential roles in protein folding and assembly of secretory proteins. ER-resident molecular chaperones and related enzymes assist in protein maturation by co-operated interactions and modifications. However, the folding/assembly of multimeric proteins is not wel...

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Detalles Bibliográficos
Autores principales: Tamura, Taku, Arai, Seisuke, Nagaya, Hisao, Mizuguchi, Jun, Wada, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769264/
https://www.ncbi.nlm.nih.gov/pubmed/24040290
http://dx.doi.org/10.1371/journal.pone.0074580