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Effect of IRS4 Levels on PI 3-Kinase Signalling

Insulin receptor substrate 1 (IRS1) and IRS2 are well-characterized adapter proteins that relay signals from receptor tyrosine kinases to downstream components of signalling pathways. In contrast, the function of IRS4 is not well understood. IRS4 overexpression has been associated with acute lymphob...

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Detalles Bibliográficos
Autores principales: Hoxhaj, Gerta, Dissanayake, Kumara, MacKintosh, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769281/
https://www.ncbi.nlm.nih.gov/pubmed/24039912
http://dx.doi.org/10.1371/journal.pone.0073327