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Effect of IRS4 Levels on PI 3-Kinase Signalling
Insulin receptor substrate 1 (IRS1) and IRS2 are well-characterized adapter proteins that relay signals from receptor tyrosine kinases to downstream components of signalling pathways. In contrast, the function of IRS4 is not well understood. IRS4 overexpression has been associated with acute lymphob...
Autores principales: | Hoxhaj, Gerta, Dissanayake, Kumara, MacKintosh, Carol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769281/ https://www.ncbi.nlm.nih.gov/pubmed/24039912 http://dx.doi.org/10.1371/journal.pone.0073327 |
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