Application of Concave Microwells to Pancreatic Tumor Spheroids Enabling Anticancer Drug Evaluation in a Clinically Relevant Drug Resistance Model

Intrinsic drug resistance of pancreatic ductal adenocarcinoma (PDAC) warrants studies using models that are more clinically relevant for identifying novel resistance mechanisms as well as for drug development. Tumor spheroids (TS) mimic in vivo tumor conditions associated with multicellular resistan...

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Detalles Bibliográficos
Autores principales: Yeon, Sang-Eun, No, Da Yoon, Lee, Sang-Hoon, Nam, Suk Woo, Oh, Il-Hoan, Lee, Jaehwi, Kuh, Hyo-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769301/
https://www.ncbi.nlm.nih.gov/pubmed/24039920
http://dx.doi.org/10.1371/journal.pone.0073345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769301/
https://www.ncbi.nlm.nih.gov/pubmed/24039920
http://dx.doi.org/10.1371/journal.pone.0073345

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