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Staphylococcus aureus Activates the NLRP3 Inflammasome in Human and Rat Conjunctival Goblet Cells

The conjunctiva is a moist mucosal membrane that is constantly exposed to an array of potential pathogens and triggers of inflammation. The NACHT, leucine rich repeat (LRR), and pyrin domain-containing protein 3 (NLRP3) is a Nod-like receptor that can sense pathogens or other triggers, and is highly...

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Detalles Bibliográficos
Autores principales: McGilligan, Victoria E., Gregory-Ksander, Meredith S., Li, Dayu, Moore, Jonathan E., Hodges, Robin R., Gilmore, Michael S., Moore, Tara C. B., Dartt, Darlene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769353/
https://www.ncbi.nlm.nih.gov/pubmed/24040145
http://dx.doi.org/10.1371/journal.pone.0074010