A Toxicogenomic Approach for the Prediction of Murine Hepatocarcinogenesis Using Ensemble Feature Selection

The current strategy for identifying the carcinogenicity of drugs involves the 2-year bioassay in male and female rats and mice. As this assay is cost-intensive and time-consuming there is a high interest in developing approaches for the screening and prioritization of drug candidates in preclinical...

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Detalles Bibliográficos
Autores principales: Eichner, Johannes, Kossler, Nadine, Wrzodek, Clemens, Kalkuhl, Arno, Bach Toft, Dorthe, Ostenfeldt, Nina, Richard, Virgile, Zell, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769381/
https://www.ncbi.nlm.nih.gov/pubmed/24040119
http://dx.doi.org/10.1371/journal.pone.0073938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769381/
https://www.ncbi.nlm.nih.gov/pubmed/24040119
http://dx.doi.org/10.1371/journal.pone.0073938

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