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Protective Effect of Hypercapnic Acidosis in Ischemia-Reperfusion Lung Injury Is Attributable to Upregulation of Heme Oxygenase-1

Hypercapnic acidosis (HCA) has protective effects in animal models of acute lung injury, but the mechanism underlying the effect of HCA is unclear. Heme oxygenase-1 (HO-1) is an antioxidant enzyme that protects tissue from inflammation injury. We investigated whether HO-1 contributes to the protecti...

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Detalles Bibliográficos
Autores principales: Wu, Shu-Yu, Li, Min-Hui, Ko, Fu-Chang, Wu, Geng-Chin, Huang, Kun-Lun, Chu, Shi-Jye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769390/
https://www.ncbi.nlm.nih.gov/pubmed/24040332
http://dx.doi.org/10.1371/journal.pone.0074742