FGF21 regulates circadian behavior and metabolism by acting on the nervous system

Fibroblast growth factor 21 (FGF21) is a hepatokine that acts as a global starvation signal to modulate fuel partitioning and metabolism, and repress growth(1); however the site of action of these diverse effects remains unclear. FGF21 signals through a heteromeric cell surface receptor composed of...

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Detalles Bibliográficos
Autores principales: Bookout, Angie L., de Groot, Marleen H. M., Owen, Bryn M., Lee, Syann, Gautron, Laurent, Lawrence, Heather L., Ding, Xunshan, Elmquist, Joel K., Takahashi, Joseph S., Mangelsdorf, David J., Kliewer, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769420/
https://www.ncbi.nlm.nih.gov/pubmed/23933984
http://dx.doi.org/10.1038/nm.3249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769420/
https://www.ncbi.nlm.nih.gov/pubmed/23933984
http://dx.doi.org/10.1038/nm.3249

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