Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus

Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively. Amino acid pattern showed that two extracts contained large amount of...

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Detalles Bibliográficos
Autores principales: Lee, June Woo, Baek, Seong Jin, Bae, Woo Chul, Park, Jeong Min, Kim, Yong Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Mycology 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769579/
https://www.ncbi.nlm.nih.gov/pubmed/24039504
http://dx.doi.org/10.4489/MYCO.2006.34.4.230
Descripción
Sumario:Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively. Amino acid pattern showed that two extracts contained large amount of aspartic acid and alanine. Two extracts showed characteristic IR absorption pattern for glycosidic bond at 890 cm(-1). PL-H was divided two fractions by gel filtration chromatography and the molecular weights of each fraction were estimated to be about 10 kD and 225 kD, respectively and also PL-A was estimated 10 kD. Two extracts showed strong antitumor, immunomodulating and antioxidant activities, and were compared with commercialized glycopeptide anticancer drugs.

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