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Metabolomic approach to evaluating adriamycin pharmacodynamics and resistance in breast cancer cells

Continuous exposure of breast cancer cells to adriamycin induces high expression of P-gp and multiple drug resistance. However, the biochemical process and the underlying mechanisms for the gradually induced resistance are not clear. To explore the underlying mechanism and evaluate the anti-tumor ef...

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Detalles Bibliográficos
Autores principales: Cao, Bei, Li, Mengjie, Zha, Weibin, Zhao, Qijin, Gu, Rongrong, Liu, Linsheng, Shi, Jian, Zhou, Jun, Zhou, Fang, Wu, Xiaolan, Wu, Zimei, Wang, Guangji, Aa, Jiye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769585/
https://www.ncbi.nlm.nih.gov/pubmed/24039617
http://dx.doi.org/10.1007/s11306-013-0517-x