Cargando…
Metabolomic approach to evaluating adriamycin pharmacodynamics and resistance in breast cancer cells
Continuous exposure of breast cancer cells to adriamycin induces high expression of P-gp and multiple drug resistance. However, the biochemical process and the underlying mechanisms for the gradually induced resistance are not clear. To explore the underlying mechanism and evaluate the anti-tumor ef...
Autores principales: | Cao, Bei, Li, Mengjie, Zha, Weibin, Zhao, Qijin, Gu, Rongrong, Liu, Linsheng, Shi, Jian, Zhou, Jun, Zhou, Fang, Wu, Xiaolan, Wu, Zimei, Wang, Guangji, Aa, Jiye |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769585/ https://www.ncbi.nlm.nih.gov/pubmed/24039617 http://dx.doi.org/10.1007/s11306-013-0517-x |
Ejemplares similares
-
Chronic Myeloid Leukemia Patients Sensitive and Resistant to Imatinib Treatment Show Different Metabolic Responses
por: A, Jiye, et al.
Publicado: (2010) -
Prediction of the Pharmacokinetic Parameters of Triptolide in Rats Based on Endogenous Molecules in Pre-Dose Baseline Serum
por: Liu, Linsheng, et al.
Publicado: (2012) -
Plasma Metabolomics Reveals Diagnostic Biomarkers and Risk Factors for Esophageal Squamous Cell Carcinoma
por: Yu, Mengjie, et al.
Publicado: (2022) -
The down-regulation of SLC7A11 enhances ROS induced P-gp over-expression and drug resistance in MCF-7 breast cancer cells
por: Ge, Chun, et al.
Publicado: (2017) -
Inhibition of P-Glycoprotein by HIV Protease Inhibitors Increases Intracellular Accumulation of Berberine in Murine and Human Macrophages
por: Zha, Weibin, et al.
Publicado: (2013)