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Addition of α-O-GlcNAc to threonine residues define the post-translational modification of mucin-like molecules in Trypanosoma cruzi

Trypanosoma cruzi, an intracellular protozoan etiologic agent of Chagas disease is covered by a dense coat of mucin-type glycoproteins, which is important to promote the parasite entry and persistence in the mammalian host cells. The O-glycosylation of T. cruzi mucins (Tc-mucins) is initiated by enz...

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Detalles Bibliográficos
Autores principales: Mendonça-Previato, Lucia, Penha, Luciana, Garcez, Tatiana Cortes, Jones, Christopher, Previato, Jose Osvaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769586/
https://www.ncbi.nlm.nih.gov/pubmed/23430107
http://dx.doi.org/10.1007/s10719-013-9469-7