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Rasagiline protects against alpha-synuclein induced sensitivity to oxidative stress in dopaminergic cells

Rasagiline is a propargylamine and irreversible monoamine oxidase (MAO) B inhibitor used for the treatment of Parkinson's disease (PD). It has demonstrated neuroprotective properties in laboratory studies. Current concepts of PD aetiopathogenesis include the role of alpha-synuclein, protein agg...

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Detalles Bibliográficos
Autores principales: Chau, K.Y., Cooper, J.M., Schapira, A.H.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769805/
https://www.ncbi.nlm.nih.gov/pubmed/20624440
http://dx.doi.org/10.1016/j.neuint.2010.06.017