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Ex Vivo Restimulation of Human PBMC Expands a CD3(+)CD4(−)CD8(−) γδ (+) T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination
The measurement of vaccine-induced humoral and CD4(+) and CD8(+) cellular immune responses represents an important correlate of vaccine efficacy. Accurate and reliable assays evaluating such responses are therefore critical during the clinical development phase of vaccines. T cells play a pivotal ro...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770040/ https://www.ncbi.nlm.nih.gov/pubmed/24066003 http://dx.doi.org/10.1155/2013/186420 |