Ex Vivo Restimulation of Human PBMC Expands a CD3(+)CD4(−)CD8(−) γδ (+) T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination

The measurement of vaccine-induced humoral and CD4(+) and CD8(+) cellular immune responses represents an important correlate of vaccine efficacy. Accurate and reliable assays evaluating such responses are therefore critical during the clinical development phase of vaccines. T cells play a pivotal ro...

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Detalles Bibliográficos
Autores principales: Sedgmen, B. J., Papalia, L., Wang, L., Dyson, A. R., McCallum, H. A., Simson, C. M., Pearse, M. J., Maraskovsky, E., Hung, D., Eomois, P. P., Hartel, G., Barnden, M. J., Rockman, S. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770040/
https://www.ncbi.nlm.nih.gov/pubmed/24066003
http://dx.doi.org/10.1155/2013/186420

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