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PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum
The variant antigen, Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), expressed on the surface of P. falciparum infected Red Blood Cells (iRBCs) is a critical virulence factor for malaria(1). Each parasite encodes 60 antigenically distinct var genes encoding PfEMP1s, but during infecti...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770130/ https://www.ncbi.nlm.nih.gov/pubmed/23823717 http://dx.doi.org/10.1038/nature12361 |