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PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum

The variant antigen, Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), expressed on the surface of P. falciparum infected Red Blood Cells (iRBCs) is a critical virulence factor for malaria(1). Each parasite encodes 60 antigenically distinct var genes encoding PfEMP1s, but during infecti...

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Detalles Bibliográficos
Autores principales: Jiang, Lubin, Mu, Jianbing, Zhang, Qingfeng, Ni, Ting, Srinivasan, Prakash, Rayavara, Kempaiah, Yang, Wenjing, Turner, Louise, Lavstsen, Thomas, Theander, Thor G., Peng, Weiqun, Wei, Guiying, Jing, Qingqing, Wakabayashi, Yoshiyuki, Bansal, Abhisheka, Luo, Yan, Ribeiro, José M.C., Scherf, Artur, Aravind, L., Zhu, Jun, Zhao, Keji, Miller, Louis H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770130/
https://www.ncbi.nlm.nih.gov/pubmed/23823717
http://dx.doi.org/10.1038/nature12361