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Testing allele homogeneity: the problem of nested hypotheses

BACKGROUND: The evaluation of associations between genotypes and diseases in a case-control framework plays an important role in genetic epidemiology. This paper focuses on the evaluation of the homogeneity of both genotypic and allelic frequencies. The traditional test that is used to check allelic...

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Detalles Bibliográficos
Autores principales: Izbicki, Rafael, Fossaluza, Victor, Hounie, Ana Gabriela, Nakano, Eduardo Yoshio, de Bragança Pereira, Carlos Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770452/
https://www.ncbi.nlm.nih.gov/pubmed/23176636
http://dx.doi.org/10.1186/1471-2156-13-103