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Testing allele homogeneity: the problem of nested hypotheses
BACKGROUND: The evaluation of associations between genotypes and diseases in a case-control framework plays an important role in genetic epidemiology. This paper focuses on the evaluation of the homogeneity of both genotypic and allelic frequencies. The traditional test that is used to check allelic...
Autores principales: | Izbicki, Rafael, Fossaluza, Victor, Hounie, Ana Gabriela, Nakano, Eduardo Yoshio, de Bragança Pereira, Carlos Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770452/ https://www.ncbi.nlm.nih.gov/pubmed/23176636 http://dx.doi.org/10.1186/1471-2156-13-103 |
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