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Novel N-phenylcarbamothioylbenzamides with anti-inflammatory activity and prostaglandin E(2) inhibitory properties

A number of 2-((4-ethylphenoxy)methyl)-N-(substituted-phenylcarbamothioyl) benzamides (1a–h) were synthesized via reaction of 2-((4-ethylphenoxy)methyl)benzoyl isothiocyanate (2) as a key intermediate with several substituted primary aromatic amines. The new compounds were characterized by proton nu...

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Detalles Bibliográficos
Autores principales: Limban, Carmen, Missir, Alexandru Vasile, Fahelelbom, Khairi Mustafa Salem, Al-Tabakha, Moawia Mohammad, Caproiu, Miron Teodor, Sadek, Bassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770517/
https://www.ncbi.nlm.nih.gov/pubmed/24039398
http://dx.doi.org/10.2147/DDDT.S46691