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Internal Ribosome Entry Segment Activity of ATXN8 Opposite Strand RNA

Spinocerebellar ataxia type 8 (SCA8) involves the expansion of CTG/CAG repeats from the overlapping ataxin 8 opposite strand (ATXN8OS) and ataxin 8 (ATXN8) genes located on chromosome 13q21. Although being transcribed, spliced and polyadenylated in the CTG orientation, ATXN8OS does not itself appear...

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Detalles Bibliográficos
Autores principales: Chen, I-Cheng, Lin, Hsuan-Yuan, Hsiao, Ya-Chin, Chen, Chiung-Mei, Wu, Yih-Ru, Shiau, Hsin-Chieh, Shen, Yu-Fang, Huang, Kuo-Shiu, Su, Ming-Tsan, Hsieh-Li, Hsiu-Mei, Lee-Chen, Guey-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770663/
https://www.ncbi.nlm.nih.gov/pubmed/24040107
http://dx.doi.org/10.1371/journal.pone.0073885