C2-Phytoceramide Perturbs Lipid Rafts and Cell Integrity in Saccharomyces cerevisiae in a Sterol-Dependent Manner

Specific ceramides are key regulators of cell fate, and extensive studies aimed to develop therapies based on ceramide-induced cell death. However, the mechanisms regulating ceramide cytotoxicity are not yet fully elucidated. Since ceramides also regulate growth and stress responses in yeast, we stu...

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Detalles Bibliográficos
Autores principales: Pacheco, Andreia, Azevedo, Flávio, Rego, António, Santos, Júlia, Chaves, Susana R., Côrte-Real, Manuela, Sousa, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770674/
https://www.ncbi.nlm.nih.gov/pubmed/24040213
http://dx.doi.org/10.1371/journal.pone.0074240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770674/
https://www.ncbi.nlm.nih.gov/pubmed/24040213
http://dx.doi.org/10.1371/journal.pone.0074240

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