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C2-Phytoceramide Perturbs Lipid Rafts and Cell Integrity in Saccharomyces cerevisiae in a Sterol-Dependent Manner

Specific ceramides are key regulators of cell fate, and extensive studies aimed to develop therapies based on ceramide-induced cell death. However, the mechanisms regulating ceramide cytotoxicity are not yet fully elucidated. Since ceramides also regulate growth and stress responses in yeast, we stu...

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Detalles Bibliográficos
Autores principales:	Pacheco, Andreia, Azevedo, Flávio, Rego, António, Santos, Júlia, Chaves, Susana R., Côrte-Real, Manuela, Sousa, Maria João
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770674/ https://www.ncbi.nlm.nih.gov/pubmed/24040213 http://dx.doi.org/10.1371/journal.pone.0074240

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