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Stochastic Stabilization of Phenotypic States: The Genetic Bistable Switch as a Case Study

We study by means of analytical calculation and stochastic simulations how intrinsic noise modifies the bifurcation diagram of gene regulatory processes that can be effectively described by the Langevin formalism. In a general context, our study raises the intriguing question of how biochemical fluc...

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Detalles Bibliográficos
Autores principales: Weber, Marc, Buceta, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770683/
https://www.ncbi.nlm.nih.gov/pubmed/24039958
http://dx.doi.org/10.1371/journal.pone.0073487