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Stochastic Stabilization of Phenotypic States: The Genetic Bistable Switch as a Case Study
We study by means of analytical calculation and stochastic simulations how intrinsic noise modifies the bifurcation diagram of gene regulatory processes that can be effectively described by the Langevin formalism. In a general context, our study raises the intriguing question of how biochemical fluc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770683/ https://www.ncbi.nlm.nih.gov/pubmed/24039958 http://dx.doi.org/10.1371/journal.pone.0073487 |