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SNP (–617C>A) in ARE-Like Loci of the NRF2 Gene: A New Biomarker for Prognosis of Lung Adenocarcinoma in Japanese Non-Smoking Women

PURPOSE: The transcription factor NRF2 plays a pivotal role in protecting normal cells from external toxic challenges and oxidative stress, whereas it can also endow cancer cells resistance to anticancer drugs. At present little information is available about the genetic polymorphisms of the NRF2 ge...

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Detalles Bibliográficos
Autores principales: Okano, Yasuko, Nezu, Uru, Enokida, Yasuaki, Lee, Ming Ta Michael, Kinoshita, Hiroko, Lezhava, Alexander, Hayashizaki, Yoshihide, Morita, Satoshi, Taguri, Masataka, Ichikawa, Yasushi, Kaneko, Takeshi, Natsumeda, Yutaka, Yokose, Tomoyuki, Nakayama, Haruhiko, Miyagi, Yohei, Ishikawa, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770684/
https://www.ncbi.nlm.nih.gov/pubmed/24040073
http://dx.doi.org/10.1371/journal.pone.0073794