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Concomitant Targeting of Multiple Key Transcription Factors Effectively Disrupts Cancer Stem Cells Enriched in Side Population of Human Pancreatic Cancer Cells

BACKGROUND: A major challenge in the treatment of pancreatic ductal adenocarcinoma is the failure of chemotherapy, which is likely due to the presence of the cancer stem cells (CSCs). OBJECTIVE: To identify side population (SP) cells and characterize s-like properties in human pancreatic cancer cell...

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Detalles Bibliográficos
Autores principales: Wang, Xiyan, Liu, Quentin, Hou, Benxin, Zhang, Wei, Yan, Min, Jia, Huimin, Li, Haijun, Yan, Dong, Zheng, Feimeng, Ding, Wei, Yi, Chao, Hai Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770686/
https://www.ncbi.nlm.nih.gov/pubmed/24040121
http://dx.doi.org/10.1371/journal.pone.0073942