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Concomitant Targeting of Multiple Key Transcription Factors Effectively Disrupts Cancer Stem Cells Enriched in Side Population of Human Pancreatic Cancer Cells
BACKGROUND: A major challenge in the treatment of pancreatic ductal adenocarcinoma is the failure of chemotherapy, which is likely due to the presence of the cancer stem cells (CSCs). OBJECTIVE: To identify side population (SP) cells and characterize s-like properties in human pancreatic cancer cell...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770686/ https://www.ncbi.nlm.nih.gov/pubmed/24040121 http://dx.doi.org/10.1371/journal.pone.0073942 |