K(ATP) Channel Opener Diazoxide Prevents Neurodegeneration: A New Mechanism of Action via Antioxidative Pathway Activation

Pharmacological modulation of ATP-sensitive potassium channels has become a promising new therapeutic approach for the treatment of neurodegenerative diseases due to their role in mitochondrial and cellular protection. For instance, diazoxide, a well-known ATP-sensitive potassium channel activator w...

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Detalles Bibliográficos
Autores principales: Virgili, Noemí, Mancera, Pilar, Wappenhans, Blanca, Sorrosal, Georgina, Biber, Knut, Pugliese, Marco, Espinosa-Parrilla, Juan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770693/
https://www.ncbi.nlm.nih.gov/pubmed/24040400
http://dx.doi.org/10.1371/journal.pone.0075189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770693/
https://www.ncbi.nlm.nih.gov/pubmed/24040400
http://dx.doi.org/10.1371/journal.pone.0075189

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