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K(ATP) Channel Opener Diazoxide Prevents Neurodegeneration: A New Mechanism of Action via Antioxidative Pathway Activation
Pharmacological modulation of ATP-sensitive potassium channels has become a promising new therapeutic approach for the treatment of neurodegenerative diseases due to their role in mitochondrial and cellular protection. For instance, diazoxide, a well-known ATP-sensitive potassium channel activator w...
Autores principales: | Virgili, Noemí, Mancera, Pilar, Wappenhans, Blanca, Sorrosal, Georgina, Biber, Knut, Pugliese, Marco, Espinosa-Parrilla, Juan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770693/ https://www.ncbi.nlm.nih.gov/pubmed/24040400 http://dx.doi.org/10.1371/journal.pone.0075189 |
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