MicroRNA-146a and RBM4 form a negative feed-forward loop that disrupts cytokine mRNA translation following TLR4 responses in human THP-1 monocytes

Within hours after its initiation, the severe systemic inflammatory response of sepsis shifts to an adaptive anti-inflammatory state with coincident immunosuppression. This anti-inflammatory phenotype is characterized by diminished proinflammatory cytokine gene expression in response to toll-like re...

Descripción completa

Detalles Bibliográficos
Autores principales: Brudecki, Laura, Ferguson, Donald A., McCall, Charles E., El Gazzar, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770753/
https://www.ncbi.nlm.nih.gov/pubmed/23897118
http://dx.doi.org/10.1038/icb.2013.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770753/
https://www.ncbi.nlm.nih.gov/pubmed/23897118
http://dx.doi.org/10.1038/icb.2013.37

Ejemplares similares