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MicroRNA-146a and RBM4 form a negative feed-forward loop that disrupts cytokine mRNA translation following TLR4 responses in human THP-1 monocytes

Within hours after its initiation, the severe systemic inflammatory response of sepsis shifts to an adaptive anti-inflammatory state with coincident immunosuppression. This anti-inflammatory phenotype is characterized by diminished proinflammatory cytokine gene expression in response to toll-like re...

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Detalles Bibliográficos
Autores principales:	Brudecki, Laura, Ferguson, Donald A., McCall, Charles E., El Gazzar, Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770753/ https://www.ncbi.nlm.nih.gov/pubmed/23897118 http://dx.doi.org/10.1038/icb.2013.37

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