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Discs Large Links Spindle Orientation to Apical-Basal Polarity in Drosophila Epithelia
Mitotic spindles in epithelial cells are oriented in the plane of the epithelium so that both daughter cells remain within the monolayer, and defects in spindle orientation have been proposed to promote tumorigenesis by causing epithelial disorganization and hyperplasia [1]. Previous work has implic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770898/ https://www.ncbi.nlm.nih.gov/pubmed/23891112 http://dx.doi.org/10.1016/j.cub.2013.07.017 |